I'm guessing you looked this up first but in case you didn't here are the minimum requirements to play minecraft:
https://help.mojang.com/customer/portal/articles/325948-minecraft-system-requirements
Minimum Requirements:
CPU : Intel P4/NetBurst Architecture or its AMD Equivalent (AMD K7)
RAM : 2GB.
GPU : Intel GMA 950 or AMD Equivalent.
HDD : At least 90MB for Game Core and Sound Files.
Java Runtime Environment (JRE) 6 or up is required to be able to run the game.
The HD 5450 is more than capable of playing the game as is demonstrated by this video:
http://www.youtube.com/watch?v=-AU0g4iTvKs
Whether you may or may not get a solid 60fps is another question. Simply put your system with that gpu can play a number of games including minecraft but again a solid 60fps or not your mileage will vary depending on the game(s). In the details of the video he is using a stronger cpu w 4GB of ram at 720p and is getting 30+fps which is still very playable.
So basically, yes, you an play a game like minecraft and your system specs meet the minimum requirements and in fact your gpu meets the recommended requirements.
Have fun!
Thanks,
Justin S.