Hi there jayr samurai,
I would say NTFS is fine. Do you have only videos on the drive or videos and programs? If you have only videos stored on the HDD and it says the drive is being used most probably it has something to do with the player you are using. Does this happen right after playing something?
It will also won't hurt if you run a testing software on the HDD to check out its health.
Cheers,
D_Know_WD