This computer can handle ANYTHING you throw at it. The CPU has 6 cores so it is perfect for work, the sli gtx 980 is much better than an sli 970 and watercooling + 2 case fans should be more than enough for cooling.
PCPartPicker part list:
http://pcpartpicker.com/p/YqNpVn
Price breakdown by merchant: http://pcpartpicker.com/p/YqNpVn/by_merchant/
CPU: Intel Core i7-5930K 3.5GHz 6-Core Processor ($563.99 @ NCIX US)
CPU Cooler: Corsair H100i 77.0 CFM Liquid CPU Cooler ($97.16 @ Amazon)
Motherboard: Asus X99-DELUXE ATX LGA2011-3 Motherboard ($357.29 @ Amazon)
Memory: Crucial Ballistix Sport 32GB (4 x 8GB) DDR4-2400 Memory ($449.99 @ Newegg)
Storage: Crucial MX100 512GB 2.5" Solid State Drive ($208.97 @ SuperBiiz)
Storage: Seagate Barracuda 3TB 3.5" 7200RPM Internal Hard Drive ($99.99 @ Amazon)
Video Card: MSI GeForce GTX 980 4GB Twin Frozr Video Card (2-Way SLI) ($585.91 @ Newegg)
Video Card: MSI GeForce GTX 980 4GB Twin Frozr Video Card (2-Way SLI) ($585.91 @ Newegg)
Case: NZXT Phantom (White) ATX Full Tower Case ($99.99 @ Micro Center)
Power Supply: XFX ProSeries 1050W 80+ Gold Certified Fully-Modular ATX Power Supply ($169.99 @ NCIX US)
Optical Drive: Asus DRW-24B1ST/BLK/B/AS DVD/CD Writer ($16.98 @ OutletPC)
Operating System: Microsoft Windows 8.1 (OEM) (64-bit) ($89.98 @ OutletPC)
Monitor: Asus VG278HE 144Hz 27.0" Monitor ($372.99 @ Amazon)
Sound Card: Asus Xonar DGX 24-bit 96 KHz Sound Card ($27.99 @ NCIX US)
Wireless Network Adapter: TP-Link TL-WDN4800 802.11a/b/g/n PCI-Express x1 Wi-Fi Adapter ($39.99 @ Amazon)
Case Fan: Cooler Master SickleFlow 69.7 CFM 120mm Fan ($2.99 @ Newegg)
Case Fan: Cooler Master SickleFlow 69.7 CFM 120mm Fan ($2.99 @ Newegg)
Keyboard: Corsair Vengeance K70 Wired Gaming Keyboard ($115.13 @ Amazon)
Mouse: Razer DeathAdder 2013 Wired Optical Mouse ($49.99 @ NCIX US)
Headphones: Logitech G430 7.1 Channel Headset ($68.99 @ Amazon)
Total: $4007.21
Prices include shipping, taxes, and discounts when available
I included a monitor which is 144hz so you can actually see fps up to 144 and you can EASILY play anything in 4k. I added a headset which is 7.1 surround sound, keyboard + gaming mouse, wireless sound card and windows 8.1 64bit so you're good to go with WHATEVER you do on the computer, this is the ultimate computer