I haven't over-clocked the card, and my settings seem pretty balanced. This issue is kind of new, didn't have it before.
And yes, I've uninstalled the GPU drivers using DDU software each time.
I guess I could try reinstalling DirectX.
Also, I've noticed on occasions that my FPS start to drop. With these settings, they are usually over 100 (120 on average, depends on the map), and then they drop to about 50-60. Seems very weird.
Edit: I'm only running one card, and I haven't experienced this issue elsewhere.
CPU: Intel i5 3570k, not over-clocked.