you can use boris's original enb with most of its effects disabled. it will inject smaa which is much more performance friendly compared to skyrims 4xMSAA or using the amd control center to force 4xMSAA. it uses its own anisotropic filter too. it also has memory management that very effectively reduces skyrims vram usage issues.
http://enbdev.com/download_mod_tesskyrim.htm
its at the bottom... v0.264
http://enbdev.com/doc_skyrim_en.htm
here is the incomplete documentation, mainly you just want to enable its AA and AF and turn memory management on for best possible performance.
as long as you dont go too crazy with graphical mods, things like huge 4k texture packs, you should have no problem getting 60fps with your fx6300+hd7850.
but at the very least you should go to nexus and get the latest unofficial skyrim patch. they are pretty well updated, also if you have the official add ons get the patches for each add on.