Of course it's a serious mobo and supports up to 32GB.
I am surprised if a mobo supports 16 I can't put 16 in 2 slots anyway :-.
As for usage, I read 40 Chrome tabs use 2,5GB.. and I wont to keep about 200 tabs active (on 2 browsers), or run 2 OS at the same time.. and I don't want to see a slow down. Guess 16GB are right for me.