You want to look at not just the speed (mhz) of the ram but also its Cas rating and then you can figure out whats the best performance.
Look at the real time latencies, not just the cycles.
Gonna steal this bit from another discussion on ram.
"1600 MHz memory at CAS 9 has a 9 cycle delay and has 1600 cycles per second. Dividing latency by frequency gives you the actual time, which is 0.005625 seconds, or 5.625ms.
1333 MHz memory at CAS 8 gives you a 6ms latency, so it will operate slightly slower. CAS 7 on the other hand, gives you 5.25ms latency, which is slightly better. "
We'll grab an example off newegg. (Going with tight timings 8-8-8-24 vs looser timings 8-10-10-24 where possible)
Crucial Ballistix Tactical 16GB DDR3 1600 Cas 8 $164
8/1600 = 5ms
Crucial Ballistix Tactical 16GB DDR3 1866 Cas 9 $169
9/1866 = 5.8ms
G.SKILL Ripjaws Z Series 16GB DDR3 2133 Cas 11 $164
11/2133 = 5.1ms
G.SKILL Trident X Series 16GB DDR3 2400 Cas 10-12-12-31 (couldn't find tighter timings than that) $139
10/2400 = 4.1ms
Now these are stock settings, chances are you can play with settings to get a bit better with some OCing. But you'd have to research out specific timings to the speed of the RAM to really get much above the stock setting of DDR 1600 Cas 8. Unless you like screwing around in your system and tinkering with settings, I'd recommend getting some solid well respected DDR 1600 Cas 8 RAM and calling it a day.