Might or might not, using what I was testing with (though this has been long known that mixing isn't a good idea) two of the manufacturers each sent two 2x8GB sets of their DRAM since they don't carry a 4x8GB set for 32GB, in both cases they wouldn't boot at spec settings. Needed to start with a single set and make voltage/timing adjustments, then they played fine...Also trid mixing a couple of sticks of a brand with a couple from another brand (identical freqs and timings) and some combos could be adjusted, though some combos just wouldn't play together at all