As long as your board has bios 1401, it will be supported out of the box. Rev. 1401 came out in Sept 2012 so a lot depends on the manufacture date for the board and when you actually bought it.
I'm not sure why some would say it's 'not a good fit' as the 'fit' depends on exactly what the use case is for the computer in the first place.
Basic server? Six sata + built in GPU.
Decent gaming system? Pretty powerful CPU + 1 PCI-e for a heavy duty video card.
I think it'll make for a decent system and Asus builds some solid mobos.