That's not enough information... Anyway you need to check and see how much of the CPU you are using (to see if it's CPU bound) and see how much spare memory you have free. My best guess is the CPU is waiting to load from and write to the HDD, if that's the case upgrading to a good SSD will help. Reading and writing from a RAM disk would be best but most people don't have money for that unless they have a Movie with major budget backing. (10K+ for a professional rendering machine with a 128GB RAM disk).