Just to elaborate on this a bit more, I could see some very specific use cases where disabling some of the cores might help since that would free up some thermal headroom. Many games aren't influenced much by having more cores, and if disabling a few of them and being able to knock up the clock speed a bit (or a bunch!) allows for those cores to run higher frequencies for longer it could benefit some games especially in a -K processor.
Easiest way to test it is this:
Leave it at stock speed (no overclock).
Leave everything stock (all cores/hyperthreading on). Check FPS.
Disable hyperthreading (again, no overclock). Check FPS.
Disable 2 cores. Check FPS
Disable 2 more cores. Check FPS.
If you get down to 2 cores, stock speed, and it doesn't change your max FPS, and your max FPS is still where you want it for gaming, then you're not CPU limited in any way, shape or form and you might as well just leave it alone.
Besides, one other thing is that remember, the chips are binned to hit their optimal speed/cores/wattage point. Going down to two cores, then jumping them up out of their peak efficiency would be pointless since power draw tends to go up exponentially when overclocking.