Yes, it is possible there is something wrong with either or both N and S bridges on your motherboard.
There is no easy way to test the motherboard by itself, that is why other components are tested to eliminate them as being possibly faulty.
As mentioned previously, try another memory in your system, and/or try the original memory in another computer. This will help determine whether the memory is faulty or maybe the motherboard is faulty.
Some other things that can be done -
Confirm video card (if used) is seated properly.
A remote possibility is that the PSU may be faulty (not supplying all power). So, could try the original PSU in another computer, and/or try another known working PSU. This will confirm or eliminate the original PSU as being faulty.