Delete this post please.

Were you asking us or telling us? I think many, including myself would disagree with the "best" part of the title.

Hot air has a natural tendency to rise. - so you are pushing the hot air inside the case in a consusing manner, with one top fan pusing into the case, the other pulling out. That would cause turbulence and impact the overall airflow. - it's also directly against the fan (blower or open fan?) of the GPU - (if we can believe the diagram). Most people that care about cooling have blowers GPUs that vent the hot air to the back. Your diagram shows a open fan setup that blows the hot air from the GPU directly into the down push of the top fan.

So yea, not the setup I'd ever build in any computer I put together.
 

Neutr1n0

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Why would you ever mount a rad in the middle of your case? There is only 2 logical setup to mount a 240 rad and that would be at the front with fans as intake or at the top with fans as exhaust.

Also you're best of using filters on all intake fans and having slightly more capacity intake than exhaust. That way your case has slight 'overpressure' and you prevent dust buildup inside your case.