Normally what happens with a CPU that has an integrated graphics chip is that when you install a discrete graphics card the integrated graphics are automatically disabled and you have to connect your monitor to the card, not the motherboard. So, if you are asking if the graphics card will still work after you put it on a motherboard that has a CPU that has integrated graphics, then yes, the graphics card should become the default video once you install it. If not, you *may* have to select it in the motherboard BIOS, but, again, most of the time the board will automatically select the card over the CPU. If you install a card that has different ports than your monitor you will need to get an adapter for one of the ports, or not use the card.
Edit: One exception to that, *IF* both the CPU and the card are compatible to run AMD Dual Graphics you can use either the card or the motherboard, though they recommend the card, from the Dual Graphics FAQ-
"Q4: Where do I plug my monitor in to get the best performance when using AMD Radeon™ Dual Graphics technology?
A4: For best performance, AMD recommends plugging the display into your discrete graphics card. This will ensure that even applications that do not take advantage of AMD Radeon™ Dual Graphics will still be able to run on the faster graphics card in your system. However, to be more accurate, we recommend that you plug your monitor into the AMD Radeon™ graphics with the higher model number. If that is your APU, plug into the motherboard, if it is your discrete graphics card, plug into that."
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