I push (3) 28" Samsung UHD with one Titan X, and I see no issues. I keep seeing "it's not going to work, and must have multiple TX in SLI"
but my setup seems to work. I am going Liquid on the Titan as the fan has to be at 60% or higher when gaming in span/surround mode... I think, and could be wrong that the PhysX combos the GPU with the CPU... That said I do run a Xeon 12 core and 32GB of DDR4
Battle Field 4 on Ultra works, I usually bring it down to High and see almost no difference other than cooler temps...
Burnout Paradise barely gets above 60 when playing... Hope this helps