meong77 :
I'm using a single OS only. I just need to know if it's practical to partition the whole 2TB into 2 parts or if i can just use it as a single whole drive.
There is no single best way, depends what you are doing with it. As usual, you folks provide less than adequate information to answer.
If I had a single 2TB drive and no other storage, I would:
Make
partition 1, for OS and Apps only, about 64G. I do this because I want to be able to disaster recover from image back ups. If anything wrong, malware, whatever, I can go back very quickly, 15 minutes, to when my OS was behaving EXACTLY what I had before. They say you can do this with Windows backup but to me it's too slow and un-reliable.
Make
partition 2, 64G or so for my TOOLS, this is where I keep stuffs I download, Apps that I've accumulated through the years, scripts, backup images etc.
Make
partition 3, 1TB for my permanent audio/video libraries, the stuff that stay pretty static.
Make
partition 4, the rest, for my daily recordings, stuffs that get added and deleted all the time, this partition will
fragment a lot.
I do these because this is my HTPC box, you have a game-only box, you will do other things.