as with everything electronic tuning and syncing will bring efficiency gains.
matching your ram speed to the native speed of mmu on the cpu is a good idea.
you get the best balance of i/o rates to bandwidth performance.
thats more important to me using an old i7. as if i go over the native mmu speed (1066/1333), the ram controller switches to 1 stick per channel. which means i would be limited to 3 sticks of ram with no ability to upgrade the other 3 unused slots.
because of this, i run my system at 3.33ghz so my ram multi can sit on 10 so i get 1333 exactly.
i could of course run the cpu faster, but i would have to drop the ram down to the next multi, and that means it would only run at 1064. if i wanted to use the other 3 sticks of ram.
so yeah for me i found there is a correlation/relationship.
also if you look at cpus speed before its multid you will see its often based 133 your ram will also have a base clock of 133.