I wish the odds were that good! Between build, upgrades and system in for other work I see well over a 100 sets a year, and I generally try mixing them with other sticks/sets. Also it should be mentioned that when sticks/sets don't want to play, one can often get them to play with voltage and timing adjustments, I spend a fair amount of time doing that here on a daily basis, but again there are no guarantees.
With all of the above, it boils down to while yes it 'may' work out, one needs to think of the counter side which may include paying return postage, restocking fees, etc not to mention not having the DRAM you want/need, all the time you might spend trying to get them to play together (not sure about you, but know my time and the time of my clients often exceeds the price and or differential in costs if one has to spend a few hours playing around w/ balky stick. So is the possibility of going through all this really worth saving $5 by getting 2 packages instead of one, when it could costs (easily more than twice the price of the single package? I don't like to put clients or anybody else in that position.