I've been told that the best bang for buck in the processor game is AMD FX series, and that although they aren't state of the art, their cache size, overclock capability and low cost make it a decent pick.
I haven't got the board or CPU yet, but I am nearly certain that is where I want to start.
Budget is <$1500, and I'm looking for performance, as I dabble in gaming a bit, but for the most part, reliability is key here.
Don't know that I want to dig into overclocking, or ramping up RAM speed, necessarily. Just wanted the ability, should I change my mind later.