A friend of mine just started playing, i5 4460/R9 255, and gets 30 ish fps at medium settings. 1080p
They just got an Nvidia patch that was supposed to be pretty significant.
The game is fairly multithreaded, moar cores helps.
There are also a fair number of Steam launch options (low memory, extremely low memory, etc)
Alpha game, pretty unoptimized, but it WILL play on your rig at some reasonable fps, and look decent.
Keep an eye on cpu/gpu temps. even on lower settings, this game makes your pc work, hard.