Yes they can be run without the fans...and the 4 series was designed for the X99 and true quad channel use the timings (secondary are more attuned towards quad channel, the V series (along with the Trident Z) is designed towards dual channel (much the same as they did with DDR3 and the Ripjaws X aimed at dual channel rigs and the Ripjaws Z towards true quad channel (X97).
Either the 4 or V will work fine with either platform, the secondary timing differences are slight