Good stuff there, although the power phases and VRMs on the motherboard could be better.
If you chip is capable of 4.6Ghz, OC Genie should get it, although you may need to tune the voltage down. Beyond that, I would want to work by hand. Using Genie makes it 'magic' and if you need to adjust things you don't know 'magic', so you are stuck. If you work by hand, you understand a great deal more about what you are doing, and are likely to get a more efficient or better overclock too.