it depends whether your case fits the 280mm rad of the H110i GTX. Personally, I would go with the H100i GTX, compatibility and performance in a package. But may I suggest other AIO's such as Thermaltake Water 3.0 Ultimate, or the Swiftech H220-X if you're quite serious about overclocking. Honestly, for OC'ing a Noctua D-15 or a Corsair H80i would be enough unless you went for the extremes.