Can Two M.2 SSDs, in Two M.2 Sockets, be Configured as Traditional "Drive C" and "Drive D"?

Avagadro1

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Oct 29, 2015
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If I purchase an "H170" motherboard (don't otherwise need the "Z170") having two M.2 SSD sockets (if available), and assuming a new/clean install of Windows 10, can those two SSDs be configured in the traditional "Drive C" and "Drive D" (main and backup) arrangement ("C", of course, being the boot drive) as I have always done with classic HDDs?
Thank you.