Okay, I see you really don't understand much about hardware. Most modern GPUs (Graphics Cards) use PCIe x16 whether it's PCIe X16 1.0, 2.0, or 3.0. ANY motherboard from 2006 and later will FOR SURE be able to handle these GPUs.
Now, you need to make sure your CPU (processor) fits into the motherboard.
Do you have a processor? Or do you need both a motherboard and a processor?