In short, yes. The board has a PCIe 3.0 slot for the GPU so the board + GPU are compatible.
It's a double-width card though, so it'll cover the next PCI slot.
You need a minimum of a 3rd gen chip to utilize PCIe 3.0 ........ a case that'll support it's near 10" length & 5" width, and a PSU at least 400W.