access will still be fast so apps (that aren't too big) will still load quickly. What you will loose is max transfer speed- it'll be limited to the max of SATA 2 (3GB/s theoretical) but in a lot of cases, you won't notice. I've run SSDs in my 1st gen asus netbook with sata 1 and it was totally usable- and WAY more performant than with a mechanical HDD.