It would require you to remove the top most drive caddy and also unscrew the mounting bracket/rails at the top of the drive caddy mounting area to clear the area for non restrictive airflow path for the AIO radiator. The next step would be to drill out slightly larger dia holes to help feed the screw into the screw mounting holes. If pulled off properly you can have one fan outside the chassis behind the front cover/plastic shroud followed by the radiator and if you wish you can run pull with another fan after the radiator.
fan<radiator<metal frame<fan<shroud
but it would have to be a 120mm radiator.
Some examples include:
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