By default, no, it won't fit well unless you position the fan a little higher on the heatsink. I did that with my Hyper 212 EVO and didn't see any changes in performance. What you can also do, and I recommend this instead, is buy your memory as 2x8Gb instead of 4x4Gb and then position them in slots 2 and 4 instead of 1 and 3. It'll cost the same or even a little cheaper to buy your memory like that. One last note is that the Hyper 212 EVO is also a big heatsink and it is only $30. The only difference you'll see then is the fans(Noctua fans are significantly better than the default on the Hyper 212 EVO)