The M.2 version is still SATA-based, so unless you need to save space from not having a 2.5" drive, no.
Full NVMe drives are around 4x faster (via PCI-E 3.0), but they're expensive, and somewhat limited by their form factor (have a look at U.2 instead - essentially an M.2 drive in 2.5" form-factor). Having said that, most/all modern SSDs are probably fast enough, anyway ...