No you shouldnt have to, however with new ram configurations you usually have to reset the CMOS, look in your motherboards manual for how to do so. One suggestion, you should go with a regular 8320 rather than the "e" skew because the e is lower powered and less performance, and they are almost the same price. Also is 32gb really nessecary. With that harware i wouldnt think you are doing massive ammounts of video editing or anything. i doubt you even peak 10gb usage all that often. Remember, as long as you arent using all your ram, adding more will not give more performance. Open task manager to see how much ram you use.