Question about PCIe 3.0

Why to motherboards frequently have verbiage like this:

For optimum performance, if only one PCI Express graphics card is to be installed, be sure to install it in the PCIEX16 slot

Isn't PCIe 3.0 x4 capable of carrying a GPU without bottlenecking? Will the new Pascal GPU's require more bandwidth than current versions?
 
Thank you both very much! Love the supplied graphs! Always wondered why Crossfire was supported and not SLI. I hate to choose a best answer. They were both great! I guess I'll have to pick TJ since he was 4 minutes quicker to to answer with those excellent graphs.