Hey there, Osiris_xiv.
Is that an OS corrupted file or you don't have any idea?
I'd suggest that you backup any important data which you might have on that drive (photos, documents, videos, etc.), just to be on the safe side. Once this is done you can go ahead and run "chkdsk". Here's how to do it:
1. Open CMD (Command Prompt) as administrator.
2. Type
chkdsk C: /r /f and press "enter"
3. Wait for the process to finish.
4. It would be nice to make a screenshot of the results and post the image here.
Other than that you should download the HDD manufacturer's diagnostic tool and test the drive for errors and bad sectors, to see if there's anything unusual.
edit: Looks like you've received another suggestion while I was typing.
Hope that helps.
Boogieman_WD