Once again one must point to how fans and air flow works.
Air flow:
pushing air through a case has to overcome the pressure drop caused by impedance. Basically pressure drop is related to air flow by the square (double flow=four times pressure)
Fan:
Fans have more or less teh reverse relation, at 0 flow it gives the most pressure, and as flow increases, pressure decreases, up to a maximum (the cfm figure you can find in specs, actually at free flow in mid air)
So, for any given setup these to curves meet at the operating point.
With two fans working in parallell, they share the flow, but still has to put in the pressure. This is done by lowering rpm until the operating point is att the same pressure, at half the flow.
Again, two fans in series (push-pull) shares the pressure, but has to give the same flow. And again, lowering rpm gives a new operating point.
It's not obvious which setup gives the lowest noise, so I agree with the above - trial and error gives the best answer. It also comes into account where the fans are placed in the case, and where the case is situated in relation to the user. (A really silent PC will sit in another room...)
/ d