2 1060s would probably be a bad idea, doesn't support SLI, which is a good reason not to get two, the second would just be defaulted for display only in most cases (there are specific cases where you can use two). Seems to me that most people round these parts are recommending the 480, they're both plenty fast for 1080, but the 480 is cheaper, even with the 8Gb RAM, which right now is overkill for 1080, but maybe in the future you would want that, also, you can crossfire the 480s, so two cards are supported in most games out of the box with little tinkering on your part. I'm waiting on the 480 for my parents' rig, I play games over there @ 1080, and the fan on their old 7870 GHz died at some point in the past few months, didn't realize it til I went over there and gave their PC a SSD and a checkup, they don't do anything graphic intensive so it never got hot without the fan... Got lucky, anyways, there's a 140mm fan zip tied to it right now...