Assuming you have the small form factor with only 1 fan like I have. Honestly, in my experience, going another 100mhz is easy and quite sustainable in my case. But do not tinker too much with memory. Even slight 50mhz increase would shake things up.
Forget about overvolting. Since the nature of the design forsake additional power, overvolting is out of the question. You're welcome to try though. Bear in mind, at full load, the whole thing sucks about 70watt. You have another 5watt as per PCI power limit, give or take, to play with.
After awhile, I choose to revert things back to default factory clock. Zotac already OC it a little bit out of the box. The difference in performance is negligible. More often than not, only a mere 2-5FPS boost. But that's in my case.
Then again, I never had the guts to push it further, since I like my stuff last for as long as possible.
@getochkn there is no such thing as a cut down 760 branded as 750Ti by any vendor. 750Ti was the earliest Maxwell implementation.