Tax6132 :
xFeaRDom :
geofelt :
I would not stress with prime95 or IBT; they use specialized instructions.
Use OCCT or an app based stress test for more realistic results.
Temperatures are not your restriction. Vcore will limit your oc.
As of 10/11/16 here are the odds of I7-6850K
overclocking at a reasonable vcore around 1.35v.
4.3 83%
4.4 53%
4.5 21%
4.6 3%
You can use Prime95, just use version 26.6 or below for more accurate results, people do prefer other software such as OCCT, which I do admit is really useful, never used Prime95 but I just stick to OCCT or the Intel one.
What should I be looking for to know if its safe or not safe to overclock more?
The main thing is temperatures. Most people have a target to aim for and go no higher, for example, mine is around 70c, some people aim for 80c, some 75 and so on. Decide what temperature makes you uncomfortable, just make sure it doesnt go above 80c altogether, as damage over long periods will be done at 85-90 to 104c, but I doubt you'll go that high.
I would bump your clock speeds up to 4GHz, then try 4.1, 4.2, all until you hit the temperature that makes you feel uncomfortable, you should be able to get a good 200, maybe 300MHz out still before you reach 70c.