OK so the picture shows exactly what I described....except when i read the 1st time, i remember the fan under the GFX card pushing in. If it's pushing air out, then you have this problem
2 fans in front minus 1/3 hit for air inlet filter restriction = 0.67 fans worth of air blowing in for each of the 2 fans
2 fan in rear blowing in with no inlet filters = 1.0 worth of fan cfm blowing air out for each of the two fans.
SO 0.67 in + 0.67 in - 1,00 out - 1,00 out = -0.67. You have negative case pressure. This means that the excess air being blown out will have to be balanced by air being sucked back in thru somewhere else and bringing more dust with it.
Also, the PSU fan **can** matter; if the case bottom doesn't have an inlet filter ? If not, the PSU fan is picking up dust, pushing it thru the PSU. Some stays, some gets puched out. What gets pushed out can wind up getting it back in because you have more case fans pushing air out then case fans pulling air in
Peeps often succumb to the notion that they need to have same air blowing in and blowing out... this is a misconception which ignores one of your cases most valuable cooling features ... the rear grille and the vented slot covers.
Kitchens get very hot and many have hoods which exhaust the hot air outside. Ever seen one that has a matching fan bringing cold air in ?
The fan creates negative pressure inside the room / building, Outside the air is higher pressure so the outside air pushes air into the kitchen, usually thru a vent or window, or if those are closed, under doors and every nook and cranny available. If you had no exhaust fans, all the air would still get out of the case... if it didn't only 2 things can happen ... a) the fans couldn't blow air in cause it had no way to get out or b) if the fans were strong enough, the case would explode.
Another example is if you have an attic fan how does that work ?
a) It takes the hot air from the highest point in your house and pushes it into the attic ... there's no other fan blowing air in
b) The attic fan blows the hot air into the attic, is no other fan blowing it out ?
So the orientation of a fan is generally determined by where the mount is: and water cooling different that air.
Water cooling, all rad fan are intakes, no exceptions.
Air Cooling
Front = In
Bottom = In
Side = in
Rear = Out
Top = It depends
if you have two fan mounts on top, if exhaust that would make 3 out ... so in order to account for the cfm loss from inlet filters, you want 1.5 times as much out... you'd need 4.5 out, say 5. If you have 2 front, 2 bottom and 1 side blowing in that works .... 5 x 2/3 = 3.33 out and 3 in... you have positive case pressure.
If they exhaust, you can remove the dust filter on top. If uses as inlets, leave them in
2 front and 2 top as intakes = 4 x 2/3 = 2.66 in and 1 out ... that means 1.33 worth of air will go out thru the rear panel grille.
It's always easier when ya name the case, but looking at the pic, it looks like an intake fan could be mounted on the bottom of the case. Assuming there's in inlet filter there, i think that would be ya best option.