I take it since you bought 16GB of the Gskill ram and two matched pairs of it @ 4GB x 4 sticks.
That you read the memory latency timings of 15-15-15-35 and wrote them down.
Along with the voltage and the speed the memory runs at of 2133 Mhx speed.
if not do so now.
Remove the Gskill memory from the system.
and insert a single stick of the crucial memory where you know the motherboard will post to the bios.
If the board is Uefi capable, then select the advanced bios setup and options mode first of all.
Now first of all look for an Xmp option in the bios that can be enabled or disabled.
You may also have an option to enable Xmp 2.0 profile mode or settings so make sure that is enabled also.
Now go to the memory section.
And manually setup or select the speed of the memory to run at 2133 Mhz.
Next look for Dram setup and timings.
Set the first three values from top to bottom to 15, 15,15. and the last value to the fourth number reference closest to
35.
Cas # latency 15
Ras # to cas # 15
Ras precharge 15
tRas 35
leave Trc set to auto.
And set the command rate of the memory to a T2 state.
Set the voltage of the new memory manually to 1.250v.
save the settings in the bios before you exit it.
Now power the system completely off.
Remove the old ram.
Get two sticks of the new Gskill memory modules.
Consulting the motherboard manual place the two sticks of memory in the first two recommended memory slot positions the manual dictates TKBurst.
Make sure both ends of the memory sticks in the memory slots of the motherboard are seated firmly and flush by using your two thumbs on each end of each memory stick making sure you hear a click of each when pushing down.
And lock the memory stick locks ether side of the memory sticks till vertical.
Now turn the system on.
If it works and the system posts, or boots to a splash screen or bios output.
Shut down the system and proceed to insert the other two Matched memory sticks to get the full 16 Gb of memory required.
As to the reason why the mix od memory modules do not work together.
It will, or is most likely that if you look at the old memory kit you will or may see that the memory chips on the ram stick only populate a single side of the board.
Where as the Gskill memory will have memory chips that populate both sides of the ram stick.
The board cannot work with a mix of memory modules where one kit of memory only has chips on one side, and when a memory stick is fitted at the same time with memory chips that populate both sides of the memory module, it has t be a full set of single sided, or dual sided populated ram sticks in each of the four memory slots of the motherboard fitted.
For the board to post to the bios splash screen.
And why the mix of memory brands do not work together ok.
SS stands for single density, single sided population
DS stands for Dual sided populated
https://ca.msi.com/Motherboard/support/Z170A-GAMING-M5.html#support_support