If the chipset, and all on board component drives are identical, then you should have no problem. If not then I would uninstall any drivers for MoBo components (LAN, Audio, etc) before taking old MoBo out.
If the system is more than a year old, you might wanna reinstall anyway to get out all the old crap and speed things up a bit ... especially if Win 10.
If ya do choose this route ....
1. Prepare for Windows installation with USB tool or use original media
https://www.microsoft.com/en-us/download/windows-usb-dvd-download-tool
2. Connect boot drive data cable to lowest numbered SATA port .... but don't connect:
-Ethernet cable
-SATA Data Cable for any other drives
3. Install Windows to boot drive
4. Turn off Windows ability to install Hardware drivers
http://www.tenforums.com/tutorials/8013-windows-update-
http://www.sevenforums.com/tutorials/82137-drivers-turn-off-automatic-driver-installation.html
5.
Install all hardware drivers from original media in boxes See Item 7 below
6. Connect ethernet cable and run Windows Update till it stops doing anything
7. Install latest drivers for ALL hardware from manufacturers web sites. The reason we didn't do this in step 5 is 3 fold:
-Sometimes MoBo CD comes with licensed utilities with product key embedded and these are not on web site versions
-Its advisable to establish a working out of box conditions
-Sometimes newer drivers require latest Windows Updates
If you have a 2nd drive ....
8. Shut down and connect HD data cable to 2nd lowest numbered SATA port.
9. Boot to BIOS and make sure that SSD is the 1st boot device, if not fix it
10. Boot to Windows and reinstall and apps / games over themselves in exact same spot (folder) if required. Some apps and games are self sufficient ... most require additional entries in registry and this is why the reinstall is necessary.
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