There are two connectors for fans that cool your CPU chip - they are CPU_FAN and CPU_OPT. IF you are using a liquid-cooling system (AIO liquid cooler) for your CPU chip, there is a special header called AIO_PUMP for that type of system. But I am not exactly sure how it needs to be used. If that is your situation, I'd suggest asking ASUS and the cooling system supplier for advice via their respective Tech Support lines.
For case ventilation fans, there are two main headers, plus a third different one. The two common ones are CHA_FAN1 and CHA_FAN2. Each of these can supply up to 1.0 amps total to all fans attached to it. Although a header is built for one fan, you can use splitters to connect more than one to a header, subject to that current limit. The third header, H_AMP_FAN, apparently does the same thing but has a higher limit on total amps. What that limit is, is not specified. The manual says that all of these fan headers (and, indeed, the ones for CPU use) can work with either 3-pin or 4-pin fans; they all are configured by default to detect the fan type connected and adjust the4mselves automatically, but you have the option on each header to set just one of those modes. This gives you lots of flexibility, but I advise one limit. On any one header if you connect more than one fan (e.g. by using a splitter), keep all the fans on one header to the same type - either 3-pin or 4-pin.
The last and not-common header is labeled EXT_FAN. This is a special header to be used only with an optional add-on card you can buy from ASUS. You connect this card to this special header, and then you can plug even more fans into that card. Without that card, this header is not to be used.
Splitters are simple devices that allow you to connect two or more fans together to one header. They can be used in either 3-pin or 4-pin fan systems. They are subject to the limit of the maximum amperage available from a header for all of the fans connected to it, because the header is the only source of power to its fans. When used, a Splitter supplies all its fans with the same power and control signals.
A different device, a 4-pin fan HUB, can be used to connect several fans to a single header. A Hub can only be used with 4-pin fan headers that use PWM Mode for control (all of yours do this) and only with 4-pin fans. Where they differ from Splitters is in power limits. A Hub gets power for all its fans from a connection directly to a PSU power output (either 4-pin Molex or SATA) and thus is not limited by the header's power limit. When used, the Hub sends the same PWM control signal from its header to all its fans.
Both Splitters and Hubs do one important thing. Any mobo fan header receives a speed pulse signal from its fan on Pin #3. It can measure and display that speed. It also can monitor that signal for fan failure. But it does NOT need that information to do its fan control functions. BUT the header can only deal with a speed pulse signal coming from ONE fan. So, all decent Splitters and Hubs will feed back to their mobo headers the signal from only ONE of their fans, and the others are ignored completely. So you will never see the speeds of the other fans on the Splitter or Hub, and the mobo cannot tell you if one of those fails.