I've been playing Skyrim on and off for a few years now and it would never fail me, running SKSE with around 130-140 mods I've never had a problem, I don't use ENB's because it's way too much for the computer, I play on a laptop which has been decent but not high end mega gaming machine but it's handled medium level skyrim graphics and a few graphical mods here and there but nothing over the top. It has an Intel Core i5-4210U CPU @2.40GHz, 16GB RAM and AMD Radeon R7 M260 graphics chipset. I stopped playing for nearly 12 months as I just didn't have time, but I started recently playing again and it is almost unplayable, very low to guess between 10-15 fps, load screens are at least 4-6 minutes each. I've taken all my mods off, nothing, started a new save, nothing, changed all settings to lowest possible, nothing, removed and reinstalled the game no mods new save low settings, still no change. I'm playing on the latest version with dragonborn, dawnguard, and hearthfire DLC. Please if I could get any help would be greatly appreciated