So I built my current PC about 2 years ago. I've had a very good experience with it. I decided to upgrade from an R9 270, to an RX 480. Personally, no compatibility issues stand out to me, except maybe the power supply. Here's my build. AMD 8350, Asus M5A97 Le, 16gb DDR3 1600, 1TB WD Blue, Rosewill ARC 550w, Windows 10. Here's what I did: Unplug everything, take side panel off, remove old gpu, installed RX 480, ran the power connector to it (it takes 8 pin, I used a 6+2) and turned the system on. It seemed fine, but the displays started to flicker. When I finally got to my desktop, I could tell that my PC was just unresponsive. I installed the new drivers via the disc that came with it, and still no sign of improvement. My CPU, HDD, and RAM were all at normal usage. Eventually, after fighting through the slow, unresponsive system, and random screen flickers, I got the blue screen with a display error code (I dont remember). A few things worth noting. the RX 480 I bought was open box, when I installed my old GPU, my system was fine. Please, I'm only an avid PC dooood so any help would be great. ALSO, before telling me to fresh install windows, I only have one hdd and would rather not go through that hassle, but hey, I'm up for anything. Thanks!