Well, for running it, I'm sure it can- but I'm not sure if you're even able to SLI those two cards. And, as well as max settings.. probably not. It's an older card, and it probably won't do so at max. In fact, cards (especially older ones) tend to be buggy when it comes to running two at once. If those are PhysX cards, you could use one in compound with a newer, better card- but, as far as using two of those go? Probably not.