Fallout 4 crashing on loading save after hardware upgrade

I have issues loading my save game from Fallout 4 after I installed my new graphics card. I went from using an AMD Radeon Sapphire HD 6670 w 1gb. I now have a GeForce FX 730 w 4gb ddr5 installed. The windows and GeForce device manager says the drivers are up to date. Any pointers?
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