Isokolon :
It depends on what you call best..
Zotac AMP Extreme & ROG Strix are the fastest but we're talking about a couple FPS, not worth it spending 50 bucks extra.
Best air cooling goes probably to the Inno3d iChill x4
Best value depends on your location but us between Gigabyte, Palit & Gainward
The EVGA ACX cards are sometimes a dB quieter
Of the 3 you've listed you can go with the cheapest one. Differences are so minor that it doesn't make a notable difference.
It does actually make a difference. Maybe not in power but definitely in noise and heat. Also, more fans doesn't equal better cooling automatically, probably why Inno3d is barely on the GPU radar. Anyone who has overclocked a founder's edition will tell you that the lack of cooling definitely hurts the performance. I even heard the 1080 Ti MSI Armor is having trouble with heat, and it has two fans.
So if you want to save yourself the headache of overheating and throttling get a cheaper card, spend the extra $50. If I had the money for a loop I would get a Sea Hawk EK X, because that is the coolest and quietest card out there, but it's an extra $150 and the loop itself is another $300-600.
Value doesn't even come into play when discussing this, because the 2-fan cards run hotter and louder than 3-fan cards in addition to not being as fast, even if only 2-4 fps, because when they throttle under heavy loads, that 2-4 fps is going to turn into 20-30 fps because of thermal throttling.
And let's talk about heatsinks for a moment. The FTW2.0 was released because of EVGA's failure to implement sufficient cooling on the FTW model, requiring thermal pads to be added. It's also evident they focused IMMENSELY on cooling for the FTW3 1080 Ti, since they went with a 3-fan card, as well as changing literally every other aspect of their cooling situations.
Asus also changed their heat-spreader and increased the size of their heatsink to increase cooling.
So why fix something that isn't broken? Because they saw deficiencies with their designs, hence the reason EVGA focused so much on cooling for the FTW3, hence why Asus changed their heat spreader and beefed up their heatsink.
So in short, yes, design makes a HUGE difference.