Answer by 9warloc9 is false. "2280" is the size of ssd in millimeters. While PCI or SATA is a logical interface of m2 slot. SATA m2 SSD will not work in PCIe m2 slot and PCIe m2 ssd will not work in SATA m2 slot.
There are several logical interfaces of m2 slot: PCI Express, SATA, USB, Display Port, I2C, SDIO, UART
There are several sizes of m2: 12, 16, 22, 30 wide, and 16, 26, 30, 38, 42, 60, 80 or 110 millimeters long.
m2 device can be one-sided or double-sided: 2280-D2-B-M means 22 mm wide, 80mm long, double-sided, suitable for slots PCIe x2 / SATA / USB / PMC / IUM / SSIC / UART-I2C