So lets suggest that it is something unrelated to the CPU, say the PCI-E slots, aside from the PCI-E lanes coming from the CPU, a fault here could lead to a short or an overvoltage condition hitting the CPU = dead CPU, ditto with many other subsystems.
So you have maybe a 60% chance of it being something wrong that does not break the CPU, 40% that it will. So use a dirt cheap CPU to test it. Then ask yourself why bother? So you test it and find it doesn't work, odds on you aren't going to be able to fix it, and you've a CPU that is working (or not) that's redundant. Or you find that it does work, and you've got a board with a dirt cheap underpowered CPU. Either way you are left out of pocket and with or without a poor system...