You'd be looking at the difference between 4.8GHz and at most 4.5GHz. This comes out to 300MHz, or ~6%. For anything that scales 100% on clock speed, your scores would be 6% lower. My guess is most games would run 3-5% slower. So instead of 60FPS, you would get 57FPS.
Keep in mind that the GPU in gaming does most of the work, so a slightly slower CPU won't make as much of a difference. And if it brings your temps and voltage down and helps your CPU to last longer than I think it's a great idea. The beauty part is because you already have all the parts you can test yourself. Run your favorite game, record the results. Dial it back to 4.5 or 4.6. How much slower is it? My guess is not enough for you to care.