I once had 2x sticks of ram. Identical in everything, vendor, model, color, speeds size, voltage everything. Except the serial number was 10 different. As in one stick was literally made 9 sticks later. That's about as close to perfectly matched ram as its possible to get in different kits. Didn't work. Totally incompatible, no timing changes, voltage changes, speed changes, nothing would get those 2x sticks to play nicely together at all. I've taken 2x different brands, from 2x different OEM (SkHynix and Micron), at 2x different speeds with 2x different timings where the only thing that was similar was the voltage. Worked like a champ at a middle speed (1600 OC to 1866, 2133 dropped to 1866) with no real effort.
That said, there is only ONE guarantee about mixing ram from different kits, there are NO guarantees. It might work, it might need adjustment, it might not work. There is simply exactly no way to tell what will happen. You might have to return several kits, just to get 1 that does work, which is a huge waste of time and frustrating beyond all belief, waiting weeks or making several trips to the store, going through rma/refund processes etc.
The only ram guaranteed to work as advertised is a full kit, no mixed ram. This is factory tested and guaranteed to work. If you decide you want to be the Guinea Pig, that's fine, test away, hope it works, but reality is your best bet to get what you want, the first time around. Just understand that multiple sticks bumps the chances of failure exponentially. Adding 1 stick to 1 stick gives @4x the chance of failure, adding 2x sticks to 2x sticks is closer to 256x the possibility of incompatibility as all 4x sticks have to be compatible at the same time.